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Bass Lab
Research in my laboratory is focused on double-stranded RNA (dsRNA)--its biological functions and the proteins that bind it to mediate these functions. At present our studies are divided between two dsRNA-mediated pathways: RNA editing by adenosine deaminases that act on RNA (ADARs), and gene-silencing (e.g., RNA interference). We anticipate future studies in additional pathways since our work suggests long, cellular dsRNA has unrecognized functions in stress, immunity and aging. More....